Microscope Market Scope Analysis And Forecast

 

What do electron microscopes, immunofluorescence, and decellularization have in common with an artist’s palette? It displays and illuminates the aesthetic beauty and the magnanimity of the material which comprises our macroscopic world.  One doesn’t have a trained scientist to grasp the beauty of an object with the zests of scientific inquiry. The hydroxyapatite crystal images captured used a scanning electron microscope and then adding a burst of colors in Photoshop conveys not only the power of electron microscopy, but also the oblivion that the organic and inorganic world share.

Since the development of the first compound microscope in the mid-sixteenth century, numerous scientists have joined forces to perfect their lenses using the technologies available at their disposal at that time. Perhaps more importantly, all the attributes of the early microscopes due to their primitiveness and the subsequent development of biological sciences, especially anatomy and botany have pushed the work of scientists to advance technology enough to realize and comprehend “the significance of the observations made.”

5 Key Types of microscopes explained

• Light Microscopes

A typical light microscope creates an optical image you see using light and are popularly used in schools, manufacturing facilities, and hospital labs. Light microscopes include inverted microscopes to study live cells or cell cultures, upright compound microscopes to view a fixed sample, stereo microscopes to generate 3-D images, and zoom microscopes to create higher resolution images thanks to an upper numerical aperture in the lens.

• Scanning Electron Microscopes (SEM)

Electron microscopes use electrons instead of visible light for image generation that bounces off to create a 3-D image of the surface. As the wavelength of electrons is smaller than visible light, it creates images with a higher resolution.  Samples placed under the scanning electron microscopes are usually coated in a thin layer of metals like gold, etc.

• Confocal Microscopes

Confocal microscopes use laser light as a light source. The laser scans the sample to create different patterns and can penetrate the sample deeper than visible light from a bulb. The resulting image is 3-D and allows you to view and examine model organisms, interior structures of cells, tissues from different optical planes, and is widely used for surface examination in quality assurance and quality control.

• Helium Ion Microscopes

Similar to a scanning electron microscope, helium ion microscopes are based on a scanning helium ion beam. Microbiologists are using it for cutting and milling of samples at sub-nanometer resolution. In terms of imaging, the helium ion microscope has several advantages over the scanning electron microscope. Owing to the short wavelength of helium ions and high source brightness the microscope can obtain qualitative data that is not achievable with conventional microscopes, which use electrons or photons as the emitting source. It provides information-rich results that offer crystallographic, topographic, electrical, and material properties of the sample.

• X-Ray Microscopes

X-ray microscopes employ electromagnetic radiation (x-rays) to generate images of minuscule objects. The x-ray microscope can be used to generate an image of living cells, unlike the scanning electron microscope as x-rays can penetrate into the depth of a sample. It can easily map the inside of samples to create a 3-D image of the inner sample structure with a very high spatial resolution.

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Eureka Alert on the top & notable developments made in the microscopes market

Artificial intelligence and Machine Learning makes great microscopes better than ever

• What could be a better catch than technology integration in healthcare facilities and infrastructure development? Artificial intelligence and machine learning makes the best microscopes work faster, see better, and process more data than ever
• Scientists are using a technique called light-field microscopy to observe the rapid neural signals in a fish brain, thus, making it possible to image such swift biological processes in 3D
• The AI algorithm has shortened the time image processing time, which earlier required days for the conversion of massive amounts of data into 3D volumes and ensuring that the resulting images are accurate and crisp

IBM unveils the world’s first-ever 2nm Chip with Nanosheet Technology and is set to serve as the underpinning of the company’s future process technology

• IBM’s new design of the world’s first-ever 2nm Chip with Nanosheet Technology is a whopping 50 billion transistors in a single chip, which is the ‘size of a fingernail’ and will benefit its partners, Intel and Samsung
• If you’re accustomed to working with an electron microscope, you’ll notice these cross-sections of transistors are markedly different from Intel’s current-gen 14nm FinFET technology. IBM’s new design will revolutionize the conventional electron microscope and announced to instigate research partner foundries in late 2024
• IBM’s 2nm process is the first to use three stacked horizontal silicon nanosheets surrounded by a ‘gate-all-around’ (GAA) technique that reduces voltage leakage EUV lithography technique to improve the yield in comparison to multi-patterning

In February 2020, as the novel coronavirus, also known as SARS-CoV-2 swept across the world and shut down entire nations, a scientist in Beijing named Sai Li set sail to paint its portrait under a cryo-electron microscope. Some researchers later used supercomputers to create comprehensive virtual images of the viruses to understand how the virus strain is spreading with such devastating ease.

NIAID’s Rocky Mountain Laboratories (RML) in Montana later unveiled images of the virus using scanning electron microscopes and transmission electron microscopes to fully decode the Covid-19 genome. Coronaviruses have been carefully studied since then and described in detail in electron microscopic images. The thin sections of the novel coronaviruses look like spherical structures with black dots on the inside with are cross-sections over the helical viral nucleocapsid.  

The Covid-19 pandemic has created a positive impact on the microscope market and experts at Grand View Research, Inc. has predicted to reach USD 16.2 billion by 2027 and expand at a CAGR of 7.9% from 2021 to 2027. Undoubtedly, technology in healthcare has become mainstream and what we know about the genomics world is just the tip of an iceberg. Scientists and healthcare professionals have put their best foot forward to wrap their heads around the fact that there are innumerable types of microorganisms yet unknown to man. While it is becoming of utmost importance to shield ourselves from the wrath of Covid-19, I at times marvel at the long way medical sciences have come today.